Immunity to the 60kD heat shock proteins

consequences for reproductive outcome

Authors

  • Andreas Neuer Cornell University Medical College

Keywords:

60kD hcat shock proteins, development, reproductive failure, preimplanracion mouse

Abstract

A brief revicw on the role of the heat shock proteins (hsp), theircommon properties and possible consequences forearly pregnancy development is described. The 60kD hsp plays an important role as immunogenic antigen of many microbial pathogens and possibly in postinfectious autoimmuniry. The immune responce to hsp may cause pregnancy failure. The consequences of previous sensitization to microbial hsp and the effects of human autoamibodies to hsp. are demonstrated in a mouse embryo culture model.

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Author Biography

Andreas Neuer, Cornell University Medical College

Departament of Obstretics and gynecology. Cornell University Medical College. USA.; Institute of ginecological endocrinology and repoductive medicine, University of Witten-Herdecke. Germany.

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Published

1998-12-01

How to Cite

1.
Neuer A. Immunity to the 60kD heat shock proteins: consequences for reproductive outcome. DST [Internet]. 1998 Dec. 1 [cited 2026 Oct. 22];10(1):17-21. Available from: https://bjstd.org/revista/article/view/207

Issue

Vol. 10 No. 1 (1998)

Section

Original Article

License

Copyright (c) 1998 Andreas Neuer

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.