HPV infection and endometriosis

a systematic review and meta-analysis

Authors

  • Geilson Gomes de Oliveira
  • José Eleutério Júnior
  • Renata Mírian Nunes Eleutério

Keywords:

papillomaviridae, endometriosis, papillomavirus infections, sexually transmitted diseases, PCR, DNA probes, HPV

Abstract

Introduction: Recent research has focused on the role of persistent ascending bacterial infections and sexually transmitted infections (STI) as a factor associated to endometriosis. Indeed, some studies investigated the possible role of HPV in endometriosis, but this topic remains inconclusive. Objective: The present study aims to meta-analyze research that assessed the presence of HPV infection in patients with endometriosis. Methods: MEDLINE, Embase, Scopus, LILACS, Cochrane Library, and OpenGrey were searched until February 10th, 2020. Search terms included “endometriosis” and “HPV” without language restrictions. The combined relative risks and 95% confidence interval (95%CI) were calculated, and heterogeneity was assessed with I-square (I2). Results: Meta-analysis with low heterogeneity found a relative risk of twice as much in women exposed to HPV in relation to the unexposed control. Conclusion: Results indicate that HPV could be a risk factor for developing endometriosis.

Downloads

Download data is not yet available.

Author Biographies

Geilson Gomes de Oliveira

Department of Pathology, Universidade Federal do Ceará – Fortaleza (CE), Brazil.

José Eleutério Júnior

Department of Pathology, Universidade Federal do Ceará – Fortaleza (CE), Brazil. Department of Women, Children, and Adolescents, Universidade Federal do Ceará – Fortaleza (CE), Brazil.

Renata Mírian Nunes Eleutério

Biomedicine Course, Centro Universitário Unichristus – Fortaleza (CE), Brazil.

Downloads

Published

2019-09-15

How to Cite

1.
Oliveira GG de, Eleutério Júnior J, Eleutério RMN. HPV infection and endometriosis: a systematic review and meta-analysis. DST [Internet]. 2019 Sep. 15 [cited 2024 Mar. 29];31(4):138-42. Available from: https://bjstd.org/revista/article/view/866

Issue

Section

Original Article