Zoon Vulvitis as a differential diagnosis of ulcerative lesions on the vulva

relato de caso

Abstract

Vulvar ulcers are a frequent reason for doubt and difficulty of etiological diagnosis. Among the causes of genital ulcers, we can mention sexually transmitted infections such as herpes simplex virus infection, syphilis, chancroid, granuloma inguinale or Donovanosis, and lymphogranuloma venereum, as well as non-infectious etiologies including psoriasis, sexual trauma, Behçet’s syndrome, Wegener’s granulomatosis, and Zoon Vulvitis. In the present study, a case of a seven months evolution genital ulcer patient (who did not respond to the various proposed therapies) was referred to the Service of Vulvar Pathology of the Hospital Universitário Antônio Pedro (Universidade Federal Fluminense). A biopsy of the lesion was performed, and the histopathological report was compatible with Zoon Vulvitis. The treatment with corticosteroids was initiated. Patient presented a successful evolution. An extensive review of the literature on differential diagnoses of vulvar ulcers was carried out in order to guide a clinical reasoning and a therapeutic approach to the different etiologies.