Does the use of probiotics in pregnant women with premature rupture of membranes improve the maternal and perinatal outcome?

a systematic review

Authors

  • Denise Vasconcelos de Moraes Universidade Federal do Ceará
  • José Eleutério Junior Universidade Federal do Ceará
  • Camylla Santos de Souza Universidade Federal do Ceará

Keywords:

probiotics, premature rupture of fetal membranes, pregnancy, microbiota

Abstract

Introduction: Premature rupture of membranes (PROM) is a condition that affects 8–10% of all pregnancies, and contributes with 20–40% of preterm deliveries. Evidence shows that changes in the vaginal microbiota may also have a favorable impact on the decrease in the prevalence of PROM, and that expectant treatment may be an appropriate approach to reduce morbidity in these cases. Objective: To investigate whether the use of probiotics in pregnant women with premature rupture of ovary membranes improves the maternal and perinatal outcome. Methods: This is a systematic review, developed from articles published between January 2001 and August 2018, which justify the use of probiotics in pregnant women with PROMto improve maternal and perinatal outcome. Results: Some studies have shown a potential role of probiotics in modulating vaginal bacterial communities, reducing rates of cesarean section and PROM, and increasing the latency and weight of newborns in pregnant women with PROM. However, in other studies, there was no confirmation of changes in the vaginal microbiota from the use of oral probiotics. Conclusion: There are benefits in the administration of probiotics to the mother-fetus binomial. However, there are still doubts about routes of administration, choice of strains and period of use. More studies are necessary to settle them.

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Author Biographies

Denise Vasconcelos de Moraes, Universidade Federal do Ceará

Maternity School Assis Chateaubriand – Fortaleza (CE), Brazil. Universidade Federal do Ceará – Fortaleza (CE), Brazil

José Eleutério Junior, Universidade Federal do Ceará

Maternity School Assis Chateaubriand – Fortaleza (CE), Brazil. Universidade Federal do Ceará – Fortaleza (CE), Brazil

Camylla Santos de Souza, Universidade Federal do Ceará

Universidade Federal do Ceará – Fortaleza (CE), Brazil.

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Published

2018-10-04

How to Cite

Moraes, D. V. de, Eleutério Junior, J., & Souza, C. S. de. (2018). Does the use of probiotics in pregnant women with premature rupture of membranes improve the maternal and perinatal outcome? a systematic review. Brazilian Journal of Sexually Transmitted Diseases, 30(3), 102–106. Retrieved from https://bjstd.org/revista/article/view/830

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Original Article