Falha no manejo sindrômico devido a Mycoplasma genitalium resistente em Florianópolis, Sul do Brasil

Autores

  • Fernando Hartmann Barazzetti Universidade Federal de Santa Catarina, Health Sciences Center, Molecular Biology, Microbiology, and Serology Laboratory (Reference Laboratory for Brazilian Gonococcal Antimicrobial Surveillance Program) – Florianópolis (SC), Brazil. https://orcid.org/0000-0001-6409-3021
  • Marcos André Schörner Universidade Federal de Santa Catarina, Health Sciences Center, Molecular Biology, Microbiology, and Serology Laboratory (Reference Laboratory for Brazilian Gonococcal Antimicrobial Surveillance Program) – Florianópolis (SC), Brazil. https://orcid.org/0000-0002-7303-6050
  • Jhonatan Augusto Ribeiro Universidade Federal de Santa Catarina, Health Sciences Center, Molecular Biology, Microbiology, and Serology Laboratory (Reference Laboratory for Brazilian Gonococcal Antimicrobial Surveillance Program) – Florianópolis (SC), Brazil. https://orcid.org/0000-0002-9222-7530
  • Henrique Borges da Silva Grisard Universidade Federal de Santa Catarina, Health Sciences Center, Molecular Biology, Microbiology, and Serology Laboratory (Reference Laboratory for Brazilian Gonococcal Antimicrobial Surveillance Program) – Florianópolis (SC), Brazil. https://orcid.org/0000-0002-7902-9548
  • Jéssica Motta Martins Universidade Federal de Santa Catarina, Health Sciences Center, Molecular Biology, Microbiology, and Serology Laboratory (Reference Laboratory for Brazilian Gonococcal Antimicrobial Surveillance Program) – Florianópolis (SC), Brazil. https://orcid.org/0000-0002-8852-7813
  • Julia Kinetz Wachter Universidade Federal de Santa Catarina, Health Sciences Center, Molecular Biology, Microbiology, and Serology Laboratory (Reference Laboratory for Brazilian Gonococcal Antimicrobial Surveillance Program) – Florianópolis (SC), Brazil. https://orcid.org/0000-0003-1681-7712
  • Patrícia de Almeida Vanny Universidade Federal de Santa Catarina, Professor Polydoro Ernani de São Thiago Universitary Hospital – Florianópolis (SC), Brazil.
  • Maria Luiza Bazzo Universidade Federal de Santa Catarina, Health Sciences Center, Molecular Biology, Microbiology, and Serology Laboratory (Reference Laboratory for Brazilian Gonococcal Antimicrobial Surveillance Program) – Florianópolis (SC), Brazil. https://orcid.org/0000-0003-1292-0974

DOI:

https://doi.org/10.5327/DST-2177-8264-2024361423

Palavras-chave:

Infecções sexualmente transmissíveis, Macrolídeos, Quinolonas, Polimorfismo de nucleotídeo único, Uretrite

Resumo

Introdução: Mycoplasma genitalium é uma bactéria associada a infecções sexualmente transmissíveis, que pode causar uretrite em homens e complicações
em mulheres, incluindo nascimento prematuro. O aumento da resistência aos macrolídeos em M. genitalium coloca desafios à eficácia do tratamento.
Objetivo: Apresentar um caso de falha terapêutica de uretrite causada por M. genitalium resistente aos macrolídeos. Relato de caso: Este relato de caso
descreve um homem de 20 anos com sintomas uretrais persistentes, apesar do tratamento com azitromicina, em que M. genitalium possuía a mutação A2058G no rRNA 23S. O tratamento subsequente com moxifloxacino resolveu os sintomas e eliminou M. genitalium. Conclusão: O estudo destacou a importância dos testes de resistência para orientar a terapia antimicrobiana e enfatizou a necessidade de atualizar as diretrizes de tratamento no Brasil.

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Publicado

2024-09-16

Como Citar

1.
Hartmann Barazzetti F, Schörner MA, Ribeiro JA, Grisard HB da S, Martins JM, Wachter JK, et al. Falha no manejo sindrômico devido a Mycoplasma genitalium resistente em Florianópolis, Sul do Brasil. DST [Internet]. 16º de setembro de 2024 [citado 27º de setembro de 2024];36. Disponível em: https://bjstd.org/revista/article/view/1423

Edição

v. 36 (2024)

Seção

Relato de caso

Licença

Copyright (c) 2024 Brazilian Journal of Sexually Transmitted Diseases

Creative Commons License
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.